PXD028126

PXD028126 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The expression of virulence and antimicrobial related proteins in different Burkholderia mallei and Burkholderia pseudomallei isolates
Description	Burkholderia mallei and Burkholderia pseudomallei are both potential biological threats agents. Melioidosis caused by B. pseudomallei is endemic in Southeast Asia and Northern Australia, while glanders caused by B. mallei infections are rare. Here we studied the proteomes of different B. mallei and B. pseudomallei isolates to determine species specific characteristics. Analyzing the expressed proteomes of B. mallei and B. pseudomallei revealed differences between B. mallei and B. pseudomallei but also between isolates from the same species. Expression of multiple virulence factors and proteins of several PKS/NRPS clusters was demonstrated. Proteome analysis can be used not only to identify bacteria but also to characterize the expression of important factors that putatively contribute to pathogenesis of B. mallei and B. pseudomallei.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:41:30.576.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD028126
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Armand Paauw
SpeciesList	scientific name: Burkholderia mallei; NCBI TaxID: 13373; scientific name: Burkholderia pseudomallei; NCBI TaxID: 28450;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-08-25 04:27:43	ID requested
1	2022-12-15 06:43:35	announced
⏵ 2	2024-10-22 05:41:30	announced	2024-10-22: Updated project metadata.

Publication List

10.6019/PXD028126;

10.6019/PXD028126;

Keyword List

submitter keyword: Burkholderia mallei Burkholderia pseudomallei proteome LC-MS/MS colony

submitter keyword: Burkholderia mallei Burkholderia pseudomallei proteome LC-MS/MS colony

Contact List

Dr. ir. A.M.J. (Annette) Kliphuis
contact affiliation	Research Manager, TNO, Department CBRN protection, The Netherlands (lab head)
contact email	annette.kliphuis@tno.nl
lab head
Armand Paauw
contact affiliation	TNO
contact email	armand.paauw@tno.nl
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/12/PXD028126
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/12/PXD028126

PRIDE project URI

Repository Record List

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