PXD028116

PXD028116 is an original dataset announced via ProteomeXchange.

Title	Salt stress downregulates 2-hydroxybutyrylation in Arabidopsis siliques
Description	In this study, we compared the siliques from Arabidopsis thaliana under salt stress (Ss) with those in the control (Cs). The results showed that Khib was abundant in siliques. However, there were certain significant differences between the Ss and the Cs: Totally 3,810 normalized Khib sites on 1,254 proteins were identified in siliques under salt stress, and Khib was up-regulated at 96 sites on 78 proteins while down-regulated at 282 sites on 205 proteins in Ss silique. Among them, 13 proteins, including F4IVN6, Q9M1P5, and Q9LF33, had sites with the most significant regulation Khib modification. Bioinformatics analysis suggests that Khib mainly participates in glycolysis/gluconeogenesis and endocytosis. In particular, there were 117 Khib-modified proteins that were mapped to the protein interaction database, and the proteins with the most significant up-regulation of Khib sites were on P46422, O82514, Q38970, Q9LD57, and Q9STW6, while the most down-regulated sites were on Q9M9K1, Q9SF16, O24456, P83484, Q9FWA3, and P54609. In the KEGG pathway enrichment analysis, Khib-modified proteins were enriched in several pathways related to energy metabolism, including gluconeogenesis pathway, pentose phosphate pathway, and pyruvate metabolism.
HostingRepository	PRIDE
AnnounceDate	2021-12-30
AnnouncementXML	Submission_2021-12-30_14:12:36.963.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Geriqiqige Hong
SpeciesList	scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationList	No PTMs are included in the dataset
Instrument	TMT quantitation analysis

Revision	Datetime	Status	ChangeLog Entry
0	2021-08-25 03:55:13	ID requested
⏵ 1	2021-12-30 14:12:37	announced

Hong G, Su X, Xu K, Liu B, Wang G, Li J, Wang R, Zhu M, Li G, Salt stress downregulates 2-hydroxybutyrylation in Arabidopsis siliques. J Proteomics, 250():104383(2022) [pubmed]

submitter keyword: Arabidopsis thaliana. Silique. Lysine 2-hydroxyisobutyrylation. Salt stress

Guojing Li
contact affiliation	Inner Mongolia Agricultural University
contact email	liguojing@imau.edu.cn
lab head
Geriqiqige Hong
contact affiliation	Inner Mongolia Key Laboratory of Plant Stress Physiology and Molecular Biology, Inner Mongolia Agricultural University
contact email	honggeriqiqige@126.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD028116
     1. Label: PRIDE project
     2. Name: Salt stress downregulates 2-hydroxybutyrylation in Arabidopsis siliques