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PXD028078

PXD028078 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePaediatric Saliva Protein Library (Burn patients and Healthy Controls) and SWATH analysis
DescriptionA paediatric saliva protein spectral library was created using drool samples collected from children with small area burn injury as well as healthy controls. Iso-electric focussing, LDS-PAGE and a combination of both fractionation methods were utilised to increase the protein coverage of the library. This resulted in the identification of 1310 proteins at a 10% FDR cut-off. The library samples were analysed using DDA-MS. The generated protein spectral library was used to quantify the abundance of 742 proteins in each individual participant sample using SWATH-MS. All samples were run on a Sciex TripleTOF 6600 mass spectrometer, and the data was processed using the OneOmics Suite v3.0 (SCIEX). Index retention time proteins were used in this experiment. The effect of burn injury and various burn characteristics on salivary protein abundance profiles were evaluated.
HostingRepositoryPRIDE
AnnounceDate2025-01-29
AnnouncementXMLSubmission_2025-01-29_01:32:27.660.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLeila Cuttle
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentTripleTOF 6600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-08-24 02:30:58ID requested
12025-01-29 01:32:28announced
Publication List
10.1002/PRCA.202300107;
Keyword List
submitter keyword: Human, burns, paediatric, saliva
Contact List
Leila Cuttle
contact affiliationCentre for Children’s Burn and Trauma Research, Centre for Children’s Health Research, Queensland University of Technology, South Brisbane, Queensland, Australia
contact emailleila.cuttle@qut.edu.au
lab head
Leila Cuttle
contact affiliationQueensland University of Technology
contact emailleila.cuttle@qut.edu.au
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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