PXD027933 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic profiling to predict therapeutic response to anti-PD1 therapy in advanced melanoma – SWATH MS dataset - glycopeptides |
Description | MS-based proteomics based on data-independent acquisition / SWATH MS was used to study the response of melanoma patients to anti-PD1 therapy. Human serum samples were collected from patients at the start of their therapy and later categorized into responders and non-responders based on clinical outcome. Samples were subjected to glycocapture and glycopeptides were quantified by SWATH MS followed by analysis using mapDIA to protein levels. |
HostingRepository | PRIDE |
AnnounceDate | 2023-08-21 |
AnnouncementXML | Submission_2023-08-21_01:24:19.045.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | LudovicGillet |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | deglycosylated asparagine; iodoacetamide derivatized residue |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-08-16 00:37:33 | ID requested | |
⏵ 1 | 2023-08-21 01:24:19 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Melanoma |
serum |
immunodepletion |
drug response |
therapeutic efficacy |
anti-PD1 therapy |
biomarker discovery |
Contact List
RuediAebersold |
contact affiliation | Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland Faculty of Science, University of Zurich, Zurich, Switzerland |
contact email | aebersold@imsb.biol.ethz.ch |
lab head | |
LudovicGillet |
contact affiliation | ETH Zurich |
contact email | gillet@imsb.biol.ethz.ch |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/08/PXD027933 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD027933
- Label: PRIDE project
- Name: Proteomic profiling to predict therapeutic response to anti-PD1 therapy in advanced melanoma – SWATH MS dataset - glycopeptides