PXD027913

PXD027913 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	PSCK9 knockdown in EndoC-bH1 cells at 72 h (DIA secretome experiment)
Description	EndoC-bH1 cells were incubated with control siRNA or PCSK9 siRNA for 72 hours. The experiment was powered based PCSK9 knockdown in the pilot experiment [PXDxxx (PE083)]. Sample size: 12x12.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:35:48.133.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Maria Ryaboshapkina
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-08-12 15:16:15	ID requested
1	2022-04-07 04:14:37	announced
2	2024-08-27 03:50:31	announced	2024-08-27: Updated project metadata.
3	2024-08-27 03:53:54	announced	2024-08-27: Updated project metadata.
⏵ 4	2024-10-22 05:35:54	announced	2024-10-22: Updated project metadata.

Publication List

10.1016/j.mcpro.2022.100229;
Saitoski K, Ryaboshapkina M, Hamza GM, Jarnuczak AF, Berthault C, Carlotti F, Armanet M, Sengupta K, Underwood CR, Andersson S, Guillas I, Le Goff W, Scharfmann R, Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intracellular and extracellular regulatory circuits. J Biol Chem, 298(7):102096(2022) [pubmed]
10.1016/j.jbc.2022.102096;
Ryaboshapkina M, Saitoski K, Hamza GM, Jarnuczak AF, Pechberty S, Berthault C, Sengupta K, Underwood CR, Andersson S, Scharfmann R, H1. Mol Cell Proteomics, 21(5):100229(2022) [pubmed]

10.1016/j.mcpro.2022.100229;

Saitoski K, Ryaboshapkina M, Hamza GM, Jarnuczak AF, Berthault C, Carlotti F, Armanet M, Sengupta K, Underwood CR, Andersson S, Guillas I, Le Goff W, Scharfmann R, Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intracellular and extracellular regulatory circuits. J Biol Chem, 298(7):102096(2022) [pubmed]

10.1016/j.jbc.2022.102096;

Ryaboshapkina M, Saitoski K, Hamza GM, Jarnuczak AF, Pechberty S, Berthault C, Sengupta K, Underwood CR, Andersson S, Scharfmann R, H1. Mol Cell Proteomics, 21(5):100229(2022) [pubmed]

Keyword List

submitter keyword: Human, PCSK9, EndoC-bH1

submitter keyword: Human, PCSK9, EndoC-bH1

Contact List

Raphael Scharfmann
contact affiliation	Université de Paris, Institut Cochin, INSERM U1016, CNRS UMR 8104, 75014 Paris, France.
contact email	raphael.scharfmann@inserm.fr
lab head
Maria Ryaboshapkina
contact affiliation	AstraZeneca
contact email	maria.ryaboshapkina@astrazeneca.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD027913
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD027913

PRIDE project URI

Repository Record List

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