PXD027834

PXD027834 is an original dataset announced via ProteomeXchange.

Title	Water-soluble tomato extract Fruitflow alters the phosphoproteomic profile of collagen-stimulated platelets
Description	The present study used proteomics to quantitatively analyze the effect of FF on the inhibition of collagen-stimulated platelets and validated the involvement of several signaling molecules.Fruitflow significantly inhibited human platelet aggregation and P-selectin expression that were induced by collagen. Proteomics analysis revealed that 60 proteins were upregulated in FF-treated collagen-stimulated platelets, and 10 proteins were downregulated in collagen-stimulated platelets alone. Additionally, 66 phosphorylated peptides were upregulated in FF-treated collagen-stimulated platelets, whereas 37 phosphorylated peptides were downregulated in collagen-stimulated platelets alone.
HostingRepository	iProX
AnnounceDate	2021-08-10
AnnouncementXML	Submission_2022-10-25_00:22:48.163.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shenghao Zhang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2021-08-09 22:10:29	ID requested
1	2021-08-09 22:10:50	announced
⏵ 2	2022-10-25 00:22:48	announced	2022-10-25: Update publication information.

Zhang S, Chen H, Li C, Chen B, Gong H, Zhao Y, Qi R, Water-Soluble Tomato Extract Fruitflow Alters the Phosphoproteomic Profile of Collagen-Stimulated Platelets. Front Pharmacol, 12():746107(2021) [pubmed]

submitter keyword: Fruitflow, platelets, proteomics

Ruomei Qi
contact affiliation	Beijing Hospital
contact email	ruomeiqi@163.com
lab head
Shenghao Zhang
contact affiliation	Beijing Hospital
contact email	18145689507@163.com
dataset submitter

iProX dataset URI