PXD027734

PXD027734 is an original dataset announced via ProteomeXchange.

Title	Proximity-biotinylation (BioID) to dissect cytoplasmic p53 signaling networks under nutrient stress
Description	p53 signaling is a major response mechanism to cellular stresses through cytoplasmic or nuclear action. While p53 protein levels have been shown to increase upon nutrient stresses such as starvation, the exact signaling cascade in this context remains elusive. Here, we use proximity biotinylation (BioID), to derive the cytoplasmic p53 interaction network as immediate early starvation response.
HostingRepository	PRIDE
AnnounceDate	2022-06-09
AnnouncementXML	Submission_2022-06-09_05:26:59.062.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Markus Galhuber
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	biotinylated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2021-08-05 08:59:22	ID requested
⏵ 1	2022-06-09 05:26:59	announced

Galhuber M, Michenthaler H, Heininger C, Reinisch I, N, ö, ssing C, Krstic J, Kupper N, Moyschewitz E, Auer M, Heitzer E, Ulz P, Birner-Gruenberger R, Liesinger L, Lenihan-Geels GN, Oster M, Spreitzer E, Zenezini Chiozzi R, Schulz TJ, Schupp M, Madl T, Heck AJR, Prokesch A, Complementary omics strategies to dissect p53 signaling networks under nutrient stress. Cell Mol Life Sci, 79(6):326(2022) [pubmed]

ProteomeXchange project tag: EPIC-XS

submitter keyword: p53 signaling, nutrient stress, starvation, interactome, BioID

Andreas Prokesch
contact affiliation	Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging Division of Cell Biology, Histology and Embryology Medical University of Graz
contact email	andreas.prokesch@medunigraz.at
lab head
Markus Galhuber
contact affiliation	Medical University of Graz
contact email	markus.galhuber@medunigraz.at
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/06/PXD027734

PRIDE project URI

• PRIDE
  1. PXD027734
     1. Label: PRIDE project
     2. Name: Proximity-biotinylation (BioID) to dissect cytoplasmic p53 signaling networks under nutrient stress