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PXD027729

PXD027729 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTrypanosoma brucei Trypanothione synthetase modification by Ebselen
DescriptionIdentification of Ebselen modification sites on T. brucei Trypanothione synthetase
HostingRepositoryPRIDE
AnnounceDate2022-05-25
AnnouncementXMLSubmission_2022-05-25_09:30:09.353.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRosario Durán
SpeciesList scientific name: Escherichia coli; NCBI TaxID: 562; scientific name: Trypanosoma brucei; NCBI TaxID: 5691;
ModificationListdihydroxylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-08-05 08:58:52ID requested
12022-05-25 09:30:12announced
Publication List
Ben, í, tez D, Franco J, Sardi F, Leyva A, Dur, á, n R, Choi G, Yang G, Kim T, Kim N, Heo J, Kim K, Lee H, Choi I, Radu C, Shum D, No JH, Comini MA, Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening. J Enzyme Inhib Med Chem, 37(1):912-929(2022) [pubmed]
Keyword List
submitter keyword: Ebselen, Trypanothione synthetase
Contact List
Rosario Durán
contact affiliationAnalytical Biochemistry and Proteomics Unit,IIBCE & Institut Pasteur de Montevideo
contact emailduran@pasteur.edu.uy
lab head
Rosario Durán
contact affiliationInstitut Pasteur de Montevideo
contact emailduran@pasteur.edu.uy
dataset submitter
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Dataset FTP location
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PRIDE project URI
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