PXD027686

PXD027686 is an original dataset announced via ProteomeXchange.

Title	Proteome characterization of glaucoma aqueous humour
Description	This work describes a proteomic analysis for different types of glaucoma (PACG, NVG) and age-related cataract as control. The AH samples were recruited from 175 individual patients with PACG, NVG and age-related cataract. First, in discovery cohort the AH proteome characteristics of PAACG, PCACG and NVG with cataract were compared by DIA approach. Second, AH proteomic features of three types of glaucoma, PAACG, PCACG and NVG, were mutually compared. In validation cohort the key proteins of above comparison were validated by PRM approach.
HostingRepository	iProX
AnnounceDate	2021-08-02
AnnouncementXML	Submission_2023-03-02_18:39:50.945.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xiaoyan Liu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion; TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2021-08-02 01:31:13	ID requested
1	2021-08-02 01:31:43	announced
⏵ 2	2023-03-02 18:39:51	announced	2023-03-03: Update publication information.

Liu X, Liu X, Wang Y, Sun H, Guo Z, Tang X, Li J, Xiao X, Zheng S, Yu M, He C, Xu J, Sun W, Proteome Characterization of Glaucoma Aqueous Humor. Mol Cell Proteomics, 20():100117(2021) [pubmed]

submitter keyword: Glaucoma, aqueous humor, proteome, molecular mechanism

Wei Sun
contact affiliation	Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College
contact email	sunwei1018@sina.com
lab head
Xiaoyan Liu
contact affiliation	Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College
contact email	xiaoyanliu.good@163.com
dataset submitter

iProX dataset URI