PXD027622

PXD027622 is an original dataset announced via ProteomeXchange.

Title	“Identifying the SLC25A46 interactome in transgenic mice: Heart"
Description	SLC25A46 is an outer mitochondrial protein, member of the mitochondrial carrier family (SLC25), whereas mutations result in mitochondrial structure abnormalities leading to a wide spectrum of neurological disorders. SLC25A46 is known to interact with members of the MICOS (Mitochondrial Contact Site) complex involved in mitochondrial cristae organization, and components of the endoplasmic reticulum membrane. In the present work, our aim was to identify the interactome of SLC25A46 in cerebrum, cerebellum, heart and thymus from TgSLC25A46-FLAG transgenic mice through immunoprecipitation with anti-FLAG beads and proteomic analysis with LC-MS/MS.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:53:21.732.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Martina Samiotaki
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-28 02:31:08	ID requested
1	2022-05-31 06:46:12	announced
⏵ 2	2023-11-14 08:53:22	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: cerebrum, heart, cerebellum, mitochondria, mouse, thymus,SLC25A46, LC-MS/MS

Eleni Douni
contact affiliation	1. Biomedical Sciences Research Center "Alexander Fleming" Athens, Greece. 2. Department of Biotechnology, Agricultural University of Athens, Athens, Greece.
contact email	douni@aua.gr
lab head
Martina Samiotaki
contact affiliation	Protein Analysis Laboratory B.S.R.C. "Alexander Fleming", Alexander Fleming Street 34 16672, Vari, Greece
contact email	samiotaki@fleming.gr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/01/PXD027622

PRIDE project URI

• PRIDE
  1. PXD027622
     1. Label: PRIDE project
     2. Name: “Identifying the SLC25A46 interactome in transgenic mice: Heart"