<<< Full experiment listing

PXD027618

PXD027618 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMass spectrometry analysis of the blood plasma and serum samples from healthy donors before and after a meal
DescriptionSerum samples were taken from four healthy donors before a meal and 3, 5, 7, 9 h after a meal (Supplementary Table S6, Sheet 1). The analysis of the serum peptidome against the HuMiProt90 database showed that the amount of non-human peptides (potentially bacterial peptides) in the bloodstream significantly increased 5 h after a meal (Figure 3D, Supplementary Table S6, Sheet 3). The comparison of these data with the transit time of food in different parts of the gastrointestinal tract suggests that bacterial peptides enter the bloodstream predominantly in the small intestine. At the same time, phyla Proteobacteria, Firmicutes and Actinobacteria are the main contributors to the increase in (potentially) bacterial peptides 5 h after a meal (Supplementary Table S6, Sheets 5 and 6).
HostingRepositoryPRIDE
AnnounceDate2024-06-14
AnnouncementXMLSubmission_2024-06-14_07:46:14.271.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD027618
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterGeorgij Arapidi
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-07-28 02:30:45ID requested
12024-06-14 07:46:14announced
Publication List
10.6019/PXD027618;
Keyword List
submitter keyword: peptidomics, human microbiota, mass spectrometry, blood plasma and serum,Healthy donors
Contact List
Georgij Pavlovich Arapidi
contact affiliationSystems Biology Laboratory, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency
contact emailarapidi@gmail.com
lab head
Georgij Arapidi
contact affiliationFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency
contact emailarapidi@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD027618
PRIDE project URI
Repository Record List
[ + ]