PXD027592 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Protein profile analysis of 12 human vitreous samples using labelfree method |
Description | To study the differences in protein profiles before and after intravitreal ranibizumab (IVR) treatment, 12 vitreous humor (VH) samples were collected from 6 proliferative diabetic retinopathy (PDR) patients before (pre group) and after IVR treatment (post group). LC–MS/MS and bioinformatics analysis were performed to identify differentially expressed proteins.Targeted proteins were validated by parallel reaction monitoring (PRM). |
HostingRepository | PRIDE |
AnnounceDate | 2022-08-12 |
AnnouncementXML | Submission_2022-08-12_07:58:51.678.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | xinping she |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-07-27 07:27:12 | ID requested | |
⏵ 1 | 2022-08-12 07:58:53 | announced | |
Publication List
She X, Zou C, Zheng Z, Differences in Vitreous Protein Profiles in Patients With Proliferative Diabetic Retinopathy Before and After Ranibizumab Treatment. Front Med (Lausanne), 9():776855(2022) [pubmed] |
Keyword List
submitter keyword: Proliferative diabetic retinopathy |
Proteomics |
Ranibizumab |
Label-free |
LC–MS/MS |
PRM |
Contact List
Zhi Zheng |
contact affiliation | Department of Ophthalmology, Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai engineering center for precise diagnosis and treatment of eye diseases |
contact email | zzheng88@sjtu.edu.cn |
lab head | |
xinping she |
contact affiliation | Department of Ophthalmology, Shanghai First People’s Hospital, School of Medicine, Shanghai Jiao Tong University |
contact email | 18916903992@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD027592
- Label: PRIDE project
- Name: Protein profile analysis of 12 human vitreous samples using labelfree method