PXD027494

PXD027494 is an original dataset announced via ProteomeXchange.

Title	Identify the specific binding partners of cytosolic TDP-43 WT and TDP-43ΔCR
Description	To investigate how translation changed as a function of TDP-43 CR loss, mass spectrometry (MS) based approach was performed to monitor the dynamics of TDP-43-associated protein complexes in response to CR deletion using TDP-43 knockout HEK293 cells expressing strep tagged wild type TDP-43 (TDP-43WT) or TDP-43ΔCR mutant.
HostingRepository	PRIDE
AnnounceDate	2022-05-20
AnnouncementXML	Submission_2022-05-20_03:17:24.404.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ju Gao
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-22 02:40:35	ID requested
⏵ 1	2022-05-20 03:17:25	announced

Gao J, Wang L, Ren X, Dunn JR, Peters A, Miyagi M, Fujioka H, Zhao F, Askwith C, Liang J, Wang X, Translational regulation in the brain by TDP-43 phase separation. J Cell Biol, 220(10):(2021) [pubmed]

submitter keyword: TDP-43, cytosolic binding partners, human cells

Xinglong Wang
contact affiliation	University of Nebraska Medical Center
contact email	xinwang@unmc.edu
lab head
Ju Gao
contact affiliation	University of Nebraska Medical Center
contact email	jugao@unmc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD027494

PRIDE project URI

• PRIDE
  1. PXD027494
     1. Label: PRIDE project
     2. Name: Identify the specific binding partners of cytosolic TDP-43 WT and TDP-43ΔCR