PXD027394

PXD027394 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification of protein-protein interactions in live cells using photoactivatable myristate probe X10
Description	19 TST-tagged myristoylated proteins (baits) were transfected into cells and labeled with photoactivatable clickable myristate probe X10. mCitrine-TST was used as a negative control. X10-labeled proteins were photocrosslinked in live cells to their interacting partners with the aim of identifying new PTM-mediated protein-protein interactions. Proteins enriched with a certain TST-tagged bait were considered interactors when compared to the presence in all other baits, with statistical significance FDR<0.05.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:52:56.934.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Roman Fedoryshchak
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	myristoylated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-18 23:57:16	ID requested
1	2023-02-04 06:54:05	announced
⏵ 2	2023-11-14 08:52:57	announced	2023-11-14: Updated project metadata.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Myristoylation
photocrosslinking
protein-protein interaction

submitter keyword: Myristoylation

photocrosslinking

protein-protein interaction

Contact List

Edward W Tate
contact affiliation	Professor of Chemical Biology, Imperial College London; Satellite Group Leader, Francis Crick Institute; Founder & SAB, Myricx Pharma Ltd; Room 301B, Molecular Sciences Research Hub, White City Campus 82 Wood Lane, London W12 0BZ, UK
contact email	e.tate@imperial.ac.uk
lab head
Roman Fedoryshchak
contact affiliation	The Francis Crick Institute
contact email	roman.fedoryshchak@crick.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD027394
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD027394

PRIDE project URI

Repository Record List

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