PXD027382
PXD027382 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Adenylyl cyclase 3 deficiency results in the dysfunction of blood-testis barrier during mouse spermiogenesis |
Description | Human infertility has become a medical and social health problem globally. Mice deficient in type 3 adenylyl cyclase (AC3), a key enzyme that synthesizes cyclic adenosine monophosphate (cAMP), develop male infertility but its underlying molecular mechanisms are still unknown. Here, we performed label-free quantitative (LFQ) proteomics study to identify testicular differentially expressed proteins (DEPs) and their respective biological processes. |
HostingRepository | iProX |
AnnounceDate | 2021-07-19 |
AnnouncementXML | Submission_2023-12-06_23:59:50.460.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Tingrong Chen |
SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-07-18 22:46:30 | ID requested | |
1 | 2021-07-18 22:52:51 | announced | |
⏵ 2 | 2023-12-06 23:59:51 | announced | 2023-12-07: Update information. |
Publication List
Chen T, Zhou Y, Liu X, Liu Y, Yuan J, Wang Z, Adenylyl cyclase 3 deficiency results in dysfunction of blood-testis barrier during mouse spermiogenesis. Theriogenology, 180():40-52(2022) [pubmed] |
Keyword List
submitter keyword: AC3, proteome, spermaotgenesis, testis, male sterility |
Contact List
Zhenshan Wang | |
---|---|
contact affiliation | Hebei University |
contact email | zswang@hbu.edu.cn |
lab head | |
Tingrong Chen | |
contact affiliation | Hebei University |
contact email | chentingrong1990@163.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |