PXD027305

PXD027305 is an original dataset announced via ProteomeXchange.

Title	First identification of Cr-binding proteome in human HepG2 cells
Description	By integrating fluorescence imaging with proteomic approach, we visualized Cr3+ protein targets mainly localized in mitochondria and identified eight Cr3+-binding proteins, including ATP synthase catalytic subunit beta (ATP5B).
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:46:07.866.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Haibo Wang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	4800 Proteomics Analyzer

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-14 07:37:17	ID requested
1	2023-05-10 13:10:56	announced
⏵ 2	2023-11-14 08:46:13	announced	2023-11-14: Updated project metadata.

Wang H, Hu L, Li H, Lai YT, Wei X, Xu X, Cao Z, Cao H, Wan Q, Chang YY, Xu A, Zhou Q, Jiang G, He ML, Sun H, Mitochondrial ATP synthase as a direct molecular target of chromium(III) to ameliorate hyperglycaemia stress. Nat Commun, 14(1):1738(2023) [pubmed]

submitter keyword: chromium, HepG2

Prof. Hongzhe Sun
contact affiliation	Department of Chemistry, The University of Hong Kong
contact email	hsun@hku.hk
lab head
Haibo Wang
contact affiliation	The University of Hong Kong
contact email	haibo_wang@connect.hku.hk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD027305

PRIDE project URI

• PRIDE
  1. PXD027305
     1. Label: PRIDE project
     2. Name: First identification of Cr-binding proteome in human HepG2 cells