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PXD027163

PXD027163 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe inflammation repressor TNIP1 is degraded by selective autophagy in a LIR-dependent manner upon TLR3 activation
DescriptionIn the project « The inflammation repressor TNIP1 is degraded by selective autophagy in a LIR-dependent manner upon TLR3 activation » Jianwen Zhou, Nikoline Lander Rasmussen, Vyacheslav Akimov, Blagoy Blagoev, Trond Lamark, Terje Johansen and Jörn Dengjel performed MS-based proteomics to study the function of TNIP1. Three set of SILAC experiments were performed (classical double-triple labeling): (1) Global analysis of ubiquitination events using the UbiSite approach. Three biological replicates were performed using following SILAC labeling (1) Protein-protein interactions of TNIP1 performing HA-TNIP1 AP-MS analyses. Three biological replicates were performed using following SILAC labeling (3) Expression proteomics comparing WT and different TNIP1 ko clones. Six biological replicates were performed using following SILAC labeling
HostingRepositoryPRIDE
AnnounceDate2022-08-07
AnnouncementXMLSubmission_2022-08-07_15:15:17.429.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJoern Dengjel
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListubiquitinylated lysine
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-07-07 07:04:41ID requested
12022-08-07 15:15:17announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: human, inflammation, LC-MSMS, SILAC
Contact List
Joern Dengjel
contact affiliationDr. Jörn Dengjel Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631 E joern.dengjel@unifr.ch
contact emailjoern.dengjel@unifr.ch
lab head
Joern Dengjel
contact affiliationUniversity of Fribourg
contact emailjoern.dengjel@medizin.uni-freiburg.de
dataset submitter
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Dataset FTP location
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