PXD027150

PXD027150 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	MALDI-TOF Profiling of modified histone proteins
Description	Histone lysine methylations as one of the chromatin post-translational modifications, has been linked to the modification of chromatin regions and mediating genome functions.In this study, we investigated the divergent role for histone H4 lysine 20 mono-methylation (H4K20me1) in facilitates chromatin openness and accessibility by disrupting chromatin folding.
HostingRepository	PRIDE
AnnounceDate	2024-10-08
AnnouncementXML	Submission_2024-10-08_11:37:39.509.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qinming Chen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monomethylated residue; N6,N6,N6-trimethyl-L-lysine
Instrument	5800 TOF/TOF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-07 02:17:04	ID requested
⏵ 1	2024-10-08 11:37:40	announced

Publication List

10.1038/s41467-021-25051-2;
Shoaib M, Chen Q, Shi X, Nair N, Prasanna C, Yang R, Walter D, Frederiksen KS, Einarsson H, Svensson JP, Liu CF, Ekwall K, Lerdrup M, Nordenski, ö, ld L, S, ø, rensen CS, Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes. Nat Commun, 12(1):4800(2021) [pubmed]

10.1038/s41467-021-25051-2;

Shoaib M, Chen Q, Shi X, Nair N, Prasanna C, Yang R, Walter D, Frederiksen KS, Einarsson H, Svensson JP, Liu CF, Ekwall K, Lerdrup M, Nordenski, ö, ld L, S, ø, rensen CS, Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes. Nat Commun, 12(1):4800(2021) [pubmed]

Keyword List

submitter keyword: MALDI-TOF

submitter keyword: MALDI-TOF

Contact List

Lars Nordenskiold
contact affiliation	school of Biological University, Nanyang Technological University, Singapore
contact email	LarsNor@ntu.edu.sg
lab head
Qinming Chen
contact affiliation	Nanyang Technological University
contact email	qmchen@ntu.edu.sg
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD027150
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD027150

PRIDE project URI

Repository Record List

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