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PXD027119

PXD027119 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAD and FTLD model mouse, brain, Phosphoproteome
DescriptionUsing a high-end mass spectrometry, we screened phosphoproteins and phosphopeptides in five types of Alzheimer's disease (AD) mouse models (5xFAD, APP-tg, PS1-tg, PS2-tg and APP-KI) and four types of frontotemporal lobar degeneration (FTLD) mouse models(CHMP2B-KI, PGRN-KI, VCP-KI and TDP43-KI) at multiple time points (1, 3 and 6 months).
HostingRepositoryPRIDE
AnnounceDate2021-09-07
AnnouncementXMLSubmission_2021-09-07_05:40:49.938.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHidenori Homma
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListphosphorylated residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-07-05 21:38:47ID requested
12021-09-07 05:40:50announced
Publication List
Jin M, Jin X, Homma H, Fujita K, Tanaka H, Murayama S, Akatsu H, Tagawa K, Okazawa H, Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis. Commun Biol, 4(1):961(2021) [pubmed]
Keyword List
submitter keyword: phosphoproteome, FTD, FTLD, AD, mouse
Contact List
Hitoshi Okazawa
contact affiliationDepartment of Neuropathology, Medical Research institute and Center for Brain Integration Research, Tokyo Medical and Dental University, Japan
contact emailokazawa-tky@umin.ac.jp
lab head
Hidenori Homma
contact affiliationTokyo Medical and Dental University
contact emailhomma.npat@mri.tmd.ac.jp
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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