PXD027090

PXD027090 is an original dataset announced via ProteomeXchange.

Title	Global quantitative proteomic analysis of aging Drosophila eyes
Description	Wild-type Drosophila melanogaster expressing nuclear GFP-KASH fusion protein in photoreceptors for cell type-specific gene expression profiling (Rh1-Gal4>UAS-GFPKASH ; Genotype = w1118;; P{w+mC=[UAS-GFP-Msp300KASH}attP2, P{ry+t7.2=rh1-GAL4}3, ry506) were raised in 12:12h light:dark cycle at 25°C. Flies were aged for 10 or 40 days post-eclosion, and eyes were harvested from male flies for global quantitative proteomic analysis. Significantly changed proteins were identified that may contribute to age-associated retinal degeneration and loss of visual function in the aging Drosophila eye.
HostingRepository	PRIDE
AnnounceDate	2021-07-23
AnnouncementXML	Submission_2021-07-22_23:03:25.664.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD027090
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Aruna Wijeratne
SpeciesList	scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-04 22:59:22	ID requested
⏵ 1	2021-07-22 23:03:26	announced

Dataset with its publication pending

submitter keyword: Drosophila, eye, aging, LC-MS/MS

Vikki M. Weake
contact affiliation	Department of Biochemistry, Purdue University, 175 S. University Street, West Lafayette, Indiana 47907, USA
contact email	vweake@purdue.edu
lab head
Aruna Wijeratne
contact affiliation	Indiana University
contact email	arwije@iu.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/07/PXD027090

PRIDE project URI

• PRIDE
  1. PXD027090
     1. Label: PRIDE project
     2. Name: Global quantitative proteomic analysis of aging Drosophila eyes