PXD027079

PXD027079 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Differences of proteome between c-MYC and L-MYC during cellular reprogramming
Description	MYC proteins (c-MYC, n-MYC, and L-MYC) are essential for improving reprogramming efficiency. L-MYC can generate iPSC colonies more efficiently than c-MYC. Still, it remains unknown what is the functional differences between c-MYC and L-MYC during cellular reprogramming. In this study, we performed proteome analysis to tackle this question and found MYC Box 0 (MB0) and 2 (MB2), one of the functional domains conserved in MYC family protein, might cause the phenotypic differences between the MYC proteins.
HostingRepository	jPOST
AnnounceDate	2022-01-08
AnnouncementXML	Submission_2022-09-18_02:59:12.533.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Iwasaki Mio
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; deamidated L-asparagine; deamidated L-glutamine; 2-pyrrolidone-5-carboxylic acid (Glu); 2-pyrrolidone-5-carboxylic acid (Gln); alpha-amino acetylated residue; Applied Biosystems iTRAQ(TM) multiplexed quantitation chemistry
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-04 00:00:27	ID requested
1	2022-01-07 07:00:09	announced
⏵ 2	2022-09-18 02:59:13	announced	2022-09-18: Updated FTP location.

Publication List

Akifuji C, Iwasaki M, Kawahara Y, Sakurai C, Cheng YS, Imai T, Nakagawa M, MYCL promotes iPSC-like colony formation via MYC Box 0 and 2 domains. Sci Rep, 11(1):24254(2021) [pubmed]

Akifuji C, Iwasaki M, Kawahara Y, Sakurai C, Cheng YS, Imai T, Nakagawa M, MYCL promotes iPSC-like colony formation via MYC Box 0 and 2 domains. Sci Rep, 11(1):24254(2021) [pubmed]

Keyword List

submitter keyword: MYC, reprogramming, proteome

submitter keyword: MYC, reprogramming, proteome

Contact List

Mio Iwasaki
lab head
Iwasaki Mio
contact affiliation	Kyoto University
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001236/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001236/