PXD027064

PXD027064 is an original dataset announced via ProteomeXchange.

Title	Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins
Description	The aim of the MS analysis is to identify fatty acids modifying Cys3 of GNAI3 in cells exposed to high C16:0 or C18:0 concentrations. Detailed description in the manuscript Nuskova et al. submitted to NatComms.
HostingRepository	PRIDE
AnnounceDate	2021-08-26
AnnouncementXML	Submission_2021-08-26_06:47:26.404.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hana Nuskova
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	palmitoylated residue; myristoylated residue
Instrument	ultraflex

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-02 08:23:59	ID requested
⏵ 1	2021-08-26 06:47:27	announced

Zhang Y, Brown K, Yu Y, Ibrahim Z, Zandian M, Xuan H, Ingersoll S, Lee T, Ebmeier CC, Liu J, Panne D, Shi X, Ren X, Kutateladze TG, Nuclear condensates of p300 formed though the structured catalytic core can act as a storage pool of p300 with reduced HAT activity. Nat Commun, 12(1):4618(2021) [pubmed]

submitter keyword: Human, GNAI3, acylation

Aurelio Teleman
contact affiliation	German Research Cancer Center (DKFZ), Heidelberg, Germany
contact email	a.teleman@dkz-heidelberg.de
lab head
Hana Nuskova
contact affiliation	DKFZ Heidelberg
contact email	h.nuskova@dkfz-heidelberg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD027064

PRIDE project URI

• PRIDE
  1. PXD027064
     1. Label: PRIDE project
     2. Name: Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins