PXD027043

PXD027043 is an original dataset announced via ProteomeXchange.

Title	Molecular insights into mechanisms of GPCR hijacking by Staphylococcus aureus
Description	We use hydrogen-deuterium exchange mass spectrometry (HDX-MS) to analyse the effects of S. aureus leucotoxins binding to the atypical chemokine receptor ACKR1 on receptor's structure and dynamics.
HostingRepository	PRIDE
AnnounceDate	2021-11-03
AnnouncementXML	Submission_2021-11-03_07:51:45.120.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Cherine Bechara
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Staphylococcus aureus subsp. aureus NN50; NCBI TaxID: 1112349;
ModificationList	sulfated residue; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-01 07:56:42	ID requested
⏵ 1	2021-11-03 07:51:46	announced

Grison CM, Lambey P, Jeannot S, Del Nero E, Fontanel S, Peysson F, Heuninck J, Sounier R, Durroux T, Leyrat C, Granier S, Bechara C, . Proc Natl Acad Sci U S A, 118(42):(2021) [pubmed]

submitter keyword: GPCR, host-pathogen interactions, structural mass spectrometry, pharmacology

Cherine Bechara
contact affiliation	IGF, University of Montpellier, CNRS, INSERM, Montpellier, France
contact email	cherine.bechara@igf.cnrs.fr
lab head
Cherine Bechara
contact affiliation	University of Montpellier
contact email	cherine.bechara@igf.cnrs.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD027043

PRIDE project URI

• PRIDE
  1. PXD027043
     1. Label: PRIDE project
     2. Name: Molecular insights into mechanisms of GPCR hijacking by Staphylococcus aureus