PXD026967

PXD026967 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Retinoic acid effect on cardiac mitochondria
Description	Using H9C2 cardiomyoblasts, we have shown that all-trans retinoic acid (ATRA), the biologically active metabolite of vitamin A, affects mitochondrial dynamics at 10nM concentration. The low dose ATRA stimulates the expression of nuclear retinoid receptors and induces mechanisms that are protective against severe point damage caused by laser irradiation at the mitochondrial level. To determine the protective effect of ATRA against photodamage, we used the proteomic analysis based on liquid chromatography and mass spectrometry (LC-MS/MS) to compare the abundancies of proteins between control and ATRA-treated cardiomyoblasts.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:53:03.405.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD026967
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Miroslav Ferko
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Bruker Daltonics amaZon series

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-28 05:01:05	ID requested
1	2022-02-22 16:28:38	announced
⏵ 2	2023-11-14 08:53:03	announced	2023-11-14: Updated project metadata.

Publication List

10.6019/PXD026967;

10.6019/PXD026967;

Keyword List

submitter keyword: mitochondria,cardiomyoblasts, all-trans retinoic acid, LC-MS/MS

submitter keyword: mitochondria,cardiomyoblasts, all-trans retinoic acid, LC-MS/MS

Contact List

Miroslav Ferko
contact affiliation	Institute for Heart Research,Centre of Experimental Medicine Slovak Academy of Sciences
contact email	miroslav.ferko@savba.sk
lab head
Miroslav Ferko
contact affiliation	Centre of Experimental Medicine, Institute for Heart Research, Slovak Academy of Sciences
contact email	miroslav.ferko@savba.sk
dataset submitter

Full Dataset Link List

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PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD026967

PRIDE project URI

Repository Record List

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