PXD026932

PXD026932 is an original dataset announced via ProteomeXchange.

Title	reductive debromination of polybrominated diphenyl ethers by Dehalococcoides
Description	Extensive use of polybrominated diphenyl ethers (PBDEs) has resulted in widespread environmental distribution and concerns remain about risks to human health and ecosystems from legacy PBDE contamination. Though bioremediation has been proven to be a cost-effective and efficient technology for treating halogenated pollutants in situ, application of bioremediation technologies at PBDE-contaminated sites is restricted by a lack of knowledge about functional PBDE-dehalogenating microbes. In the current study, we observed distinct PBDE-dehalogenation activity by three previously isolated Dehalococcoides mccartyi strains (CG1, CG4, and 11a5). PBDE debromination proceeded via distinct pathways in each D. mccartyi strain and involved previously characterized (TceA11a5, PcbA1, and PcbA4) and uncharacterized (11a5_e001) reductive dehalogenases (RDase), suggesting that this phenotype may be more widespread among the Dehalococcoides than is currently recognized.
HostingRepository	PRIDE
AnnounceDate	2022-05-26
AnnouncementXML	Submission_2022-05-25_18:39:57.197.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Siyan Zhao
SpeciesList	scientific name: Dehalococcoides mccartyi CG1; NCBI TaxID: 1432059; scientific name: Dehalococcoides mccartyi; NCBI TaxID: 61435;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-25 03:55:02	ID requested
⏵ 1	2022-05-25 18:39:57	announced

Dataset with its publication pending

submitter keyword: reductive dehalogenation, polybrominated diphenyl ethers, Dehalococcoides

He Jianzhong
contact affiliation	Department of Civil and Environmental Engineering, National University of Singapore
contact email	jianzhong.he@nus.edu.sg
lab head
Siyan Zhao
contact affiliation	National University of Singapore
contact email	siyan.zhao@outlook.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD026932

PRIDE project URI

• PRIDE
  1. PXD026932
     1. Label: PRIDE project
     2. Name: reductive debromination of polybrominated diphenyl ethers by Dehalococcoides