PXD026910 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic analysis of adipose tissue from a pig model of mutant INS gene induced diabetes of youth (MIDY) |
Description | To evaluate functional consequences of insulin-deficient diabetes mellitus for adipose tissue, we used a genetically engineered pig model of mutant INS gene induced diabetes of youth (MIDY). Adipose tissue samples of MIDY pigs and wild-type (WT) littermate controls were analyzed by label-free proteomics to reveal pathways and key drivers significantly affected by chronic insulin deficiency and hyperglycemia. |
HostingRepository | PRIDE |
AnnounceDate | 2022-02-17 |
AnnouncementXML | Submission_2022-02-17_04:52:23.648.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Florian Flenkenthaler |
SpeciesList | scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-06-24 06:54:41 | ID requested | |
⏵ 1 | 2022-02-17 04:52:24 | announced | |
Publication List
Flenkenthaler F, L, ä, ndstr, ö, m E, Shashikadze B, Backman M, Blutke A, Philippou-Massier J, Renner S, Hrabe de Angelis M, Wanke R, Blum H, Arnold GJ, Wolf E, Fr, ö, hlich T, Differential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue-Multi-omics Insights From the Munich MIDY Pig Model. Front Med (Lausanne), 8():751277(2021) [pubmed] |
Keyword List
submitter keyword: Diabetes, Animal model, Pig model, MIDY, Biobank, Adipose tissue, LC-MS/MS |
Contact List
Thomas Fröhlich |
contact affiliation | Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany |
contact email | frohlich@genzentrum.lmu.de |
lab head | |
Florian Flenkenthaler |
contact affiliation | Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany |
contact email | flenkenthaler@genzentrum.lmu.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD026910 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD026910
- Label: PRIDE project
- Name: Proteomic analysis of adipose tissue from a pig model of mutant INS gene induced diabetes of youth (MIDY)