PXD026851

PXD026851 is an original dataset announced via ProteomeXchange.

Title	Identification of PRMT1 interaction proteins in cancer and neural stem cells
Description	We have showed that cancer cells (or tumorigenic cells) resemble neural stem/progenitor cells in regulatory network, tumorigenicity and differentiation potential. We have shown PRMT1 is a protein that is upreguated in and promotes vaious cancers. The expression of its gene is localized to embryonic neural cells during vertebrate embryogenesis. The project is to identify the interaction partners of PRMT1, by which PRMT1 regulates neural stemness in both cancer cells and neural stem cells.
HostingRepository	PRIDE
AnnounceDate	2021-12-20
AnnouncementXML	Submission_2021-12-20_11:40:33.112.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ying Cao
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-21 22:44:02	ID requested
⏵ 1	2021-12-20 11:40:33	announced

Chen L, Zhang M, Fang L, Yang X, Cao N, Xu L, Shi L, Cao Y, Coordinated regulation of the ribosome and proteasome by PRMT1 in the maintenance of neural stemness in cancer cells and neural stem cells. J Biol Chem, 297(5):101275(2021) [pubmed]

submitter keyword: PRMT1, HepG2, NE-4C, LC-MS/MS

Ying Cao
contact affiliation	Model Animal Research Center, Medical School, Nanjing University
contact email	caoying@nju.edu.cn
lab head
Ying Cao
contact affiliation	Nanjing University
contact email	caoying@nju.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/12/PXD026851

PRIDE project URI

• PRIDE
  1. PXD026851
     1. Label: PRIDE project
     2. Name: Identification of PRMT1 interaction proteins in cancer and neural stem cells