PXD026851 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identification of PRMT1 interaction proteins in cancer and neural stem cells |
Description | We have showed that cancer cells (or tumorigenic cells) resemble neural stem/progenitor cells in regulatory network, tumorigenicity and differentiation potential. We have shown PRMT1 is a protein that is upreguated in and promotes vaious cancers. The expression of its gene is localized to embryonic neural cells during vertebrate embryogenesis. The project is to identify the interaction partners of PRMT1, by which PRMT1 regulates neural stemness in both cancer cells and neural stem cells. |
HostingRepository | PRIDE |
AnnounceDate | 2021-12-20 |
AnnouncementXML | Submission_2021-12-20_11:40:33.112.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Ying Cao |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-06-21 22:44:02 | ID requested | |
⏵ 1 | 2021-12-20 11:40:33 | announced | |
Publication List
Chen L, Zhang M, Fang L, Yang X, Cao N, Xu L, Shi L, Cao Y, Coordinated regulation of the ribosome and proteasome by PRMT1 in the maintenance of neural stemness in cancer cells and neural stem cells. J Biol Chem, 297(5):101275(2021) [pubmed] |
Keyword List
submitter keyword: PRMT1, HepG2, NE-4C, LC-MS/MS |
Contact List
Ying Cao |
contact affiliation | Model Animal Research Center, Medical School, Nanjing University |
contact email | caoying@nju.edu.cn |
lab head | |
Ying Cao |
contact affiliation | Nanjing University |
contact email | caoying@nju.edu.cn |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/12/PXD026851 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD026851
- Label: PRIDE project
- Name: Identification of PRMT1 interaction proteins in cancer and neural stem cells