PXD026818

PXD026818 is an original dataset announced via ProteomeXchange.

Title	CD68+ region of rat scar tissue by AutoSTOMP
Description	To test the ability of the Automated Spatially Targeted Optical Micro Proteomics (AutoSTOMP) protocol to selectively biotinylate structures of interest within tissue sections we first examined a rat myocardial infarction model. In this model, trauma caused by ligation and infiltrating immune cells causes fibroblast activation and deposition of scar tissue that ultimately impairs cardiac function. Macrophages are thought to play a role in inflammatory regulation and damaged cell turnover in the tissue. We decide to grab the proteome of the macrophage rich regions.
HostingRepository	PRIDE
AnnounceDate	2021-08-10
AnnouncementXML	Submission_2021-09-15_23:21:25.914.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	BOCHENG YIN
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	biotinylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-20 22:44:40	ID requested
1	2021-08-10 07:52:50	announced
⏵ 2	2021-09-15 23:21:26	announced	2021-09-16: Updated publication reference for PubMed record(s): 34436902.

Yin B, Caggiano LR, Li RC, McGowan E, Holmes JW, Ewald SE, . J Proteome Res, 20(9):4543-4552(2021) [pubmed]

submitter keyword: rat cardiac scar, macrophage, autoSTOMP

Sarah E. Ewald
contact affiliation	University of Virginia
contact email	se2s@virginia.edu
lab head
BOCHENG YIN
contact affiliation	University of Virginia
contact email	yincool2008@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD026818

PRIDE project URI

• PRIDE
  1. PXD026818
     1. Label: PRIDE project
     2. Name: CD68+ region of rat scar tissue by AutoSTOMP