PXD026816

PXD026816 is an original dataset announced via ProteomeXchange.

Title	Comparative Proteomic Analysis of retro-oil fluid and vitreous fluid from patients
Description	There have been reports of unexplained visual loss following intra-ocular silicone oil (SiO) tamponade in retinal detachment patients, yet the underlying mechanism is unknown. In the present study, we identified differentially expressed proteins in the vitreous humor of four groups (each group, n=3): pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RD group), SiO removal after successful retinal reattachment (SO group), cataract surgery after successful retinal reattachment with sterilized air tamponade (FA group), and PPV for epiretinal membrane (ERM group). DIA was combined with two-dimensional liquid chromatography-tandem mass spectrometry (LC-MS/MS) to find expression changes in the proteome of vitreous.
HostingRepository	PRIDE
AnnounceDate	2022-02-17
AnnouncementXML	Submission_2022-02-17_04:46:22.553.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yiyang Shu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-20 22:41:21	ID requested
⏵ 1	2022-02-17 04:46:23	announced

Shu Y, Gao M, Zhou Y, Liu H, Sun X, DIA Comparative Proteomic Analysis of Retro-oil Fluid and Vitreous Fluid From Retinal Detachment Patients. Front Mol Biosci, 8():763002(2021) [pubmed]

submitter keyword: Human；vitreous；DIA

Haiyun Liu
contact affiliation	1Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China,
contact email	drliuhaiyun@126.com
lab head
Yiyang Shu
contact affiliation	Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
contact email	shuyiyang@sjtu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD026816

PRIDE project URI

• PRIDE
  1. PXD026816
     1. Label: PRIDE project
     2. Name: Comparative Proteomic Analysis of retro-oil fluid and vitreous fluid from patients