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PXD026816

PXD026816 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComparative Proteomic Analysis of retro-oil fluid and vitreous fluid from patients
DescriptionThere have been reports of unexplained visual loss following intra-ocular silicone oil (SiO) tamponade in retinal detachment patients, yet the underlying mechanism is unknown. In the present study, we identified differentially expressed proteins in the vitreous humor of four groups (each group, n=3): pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RD group), SiO removal after successful retinal reattachment (SO group), cataract surgery after successful retinal reattachment with sterilized air tamponade (FA group), and PPV for epiretinal membrane (ERM group). DIA was combined with two-dimensional liquid chromatography-tandem mass spectrometry (LC-MS/MS) to find expression changes in the proteome of vitreous.
HostingRepositoryPRIDE
AnnounceDate2022-02-17
AnnouncementXMLSubmission_2022-02-17_04:46:22.553.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYiyang Shu
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-06-20 22:41:21ID requested
12022-02-17 04:46:23announced
Publication List
Shu Y, Gao M, Zhou Y, Liu H, Sun X, DIA Comparative Proteomic Analysis of Retro-oil Fluid and Vitreous Fluid From Retinal Detachment Patients. Front Mol Biosci, 8():763002(2021) [pubmed]
Keyword List
submitter keyword: Human;vitreous;DIA
Contact List
Haiyun Liu
contact affiliation1Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China,
contact emaildrliuhaiyun@126.com
lab head
Yiyang Shu
contact affiliationDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
contact emailshuyiyang@sjtu.edu.cn
dataset submitter
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Dataset FTP location
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