PXD026802

PXD026802 is an original dataset announced via ProteomeXchange.

Title	Deep proteome profiling of human cerebrospinal fluid from patients diagnosed with Multiple System Atrophy, Parkinson’s Disease, Dementia with Lewy Bodies, Progressive Supranuclear Palsy, and from Controls
Description	Human cerebrospinal fluid was collected from patients diagnosed with neurodegenerative diseases including multiple system atrophy (n=28), Parkinson’s disease (n=40), dementia with Lewy bodies (n=20), progressive supranuclear palsy (n=39) and from controls (n=17) in order to perform a comparative quantitative proteome profiling of cerebrospinal fluids from the five groups.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:39:09.097.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ole Østergaard
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-18 06:04:29	ID requested
1	2022-08-12 15:13:28	announced
⏵ 2	2024-10-22 05:39:10	announced	2024-10-22: Updated project metadata.

10.1007/s00018-022-04378-z;

Rydbirk R, Ø, stergaard O, Folke J, Hempel C, DellaValle B, Andresen TL, L, ø, kkegaard A, Hejl AM, Bode M, Blaabjerg M, M, ø, ller M, Danielsen EH, Salvesen L, Starhof CC, Bech S, Winge K, Rungby J, Pakkenberg B, Brudek T, Olsen JV, Aznar S, Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology. Cell Mol Life Sci, 79(6):336(2022) [pubmed]

submitter keyword: Human, cerebrospinal fluid, Q-Exactive HF-X, Parkinson’s Disease, mass spectrometry, EvoSep, Multiple System Atrophy, Progressive Supranuclear Palsy, proteome, Dementia with Lewy Bodies

Jesper Velgaard Olsen
contact affiliation	Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark
contact email	jesper.olsen@cpr.ku.dk
lab head
Ole Østergaard
contact affiliation	Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark
contact email	ole.ostergaard@cpr.ku.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD026802

PRIDE project URI

• PRIDE
  1. PXD026802
     1. Label: PRIDE project
     2. Name: Deep proteome profiling of human cerebrospinal fluid from patients diagnosed with Multiple System Atrophy, Parkinson’s Disease, Dementia with Lewy Bodies, Progressive Supranuclear Palsy, and from Controls