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PXD026802

PXD026802 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDeep proteome profiling of human cerebrospinal fluid from patients diagnosed with Multiple System Atrophy, Parkinson’s Disease, Dementia with Lewy Bodies, Progressive Supranuclear Palsy, and from Controls
DescriptionHuman cerebrospinal fluid was collected from patients diagnosed with neurodegenerative diseases including multiple system atrophy (n=28), Parkinson’s disease (n=40), dementia with Lewy bodies (n=20), progressive supranuclear palsy (n=39) and from controls (n=17) in order to perform a comparative quantitative proteome profiling of cerebrospinal fluids from the five groups.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:39:09.097.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterOle Østergaard
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-06-18 06:04:29ID requested
12022-08-12 15:13:28announced
22024-10-22 05:39:10announced2024-10-22: Updated project metadata.
Publication List
10.1007/s00018-022-04378-z;
Rydbirk R, Ø, stergaard O, Folke J, Hempel C, DellaValle B, Andresen TL, L, ø, kkegaard A, Hejl AM, Bode M, Blaabjerg M, M, ø, ller M, Danielsen EH, Salvesen L, Starhof CC, Bech S, Winge K, Rungby J, Pakkenberg B, Brudek T, Olsen JV, Aznar S, Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology. Cell Mol Life Sci, 79(6):336(2022) [pubmed]
Keyword List
submitter keyword: Human, cerebrospinal fluid, Q-Exactive HF-X, Parkinson’s Disease, mass spectrometry, EvoSep, Multiple System Atrophy, Progressive Supranuclear Palsy, proteome, Dementia with Lewy Bodies
Contact List
Jesper Velgaard Olsen
contact affiliationNovo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark
contact emailjesper.olsen@cpr.ku.dk
lab head
Ole Østergaard
contact affiliationNovo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark
contact emailole.ostergaard@cpr.ku.dk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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