PXD026771

PXD026771 is an original dataset announced via ProteomeXchange.

Title	Skeletal muscle wt and OXPHOS inhibited 18 months-old mice
Description	TMT sixplex Isobaric Mass Tagging (TAM) analysis was carried out in the CBMSO Protein Chemistry Facility (ProteoRed, PRB3-ISCIII and UAM University, Spain. Chronic skeletal muscle mitochondria dyshomeostasis drives tubular aggregate formation.
HostingRepository	PRIDE
AnnounceDate	2022-08-12
AnnouncementXML	Submission_2022-08-12_03:24:15.116.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD026771
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Cristina Sánchez González
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-18 01:28:05	ID requested
⏵ 1	2022-08-12 03:24:16	announced

S, á, nchez-Gonz, á, lez C, Herrero Mart, í, n JC, Salegi Ansa B, N, ú, ñ, ez de Arenas C, Stan, č, i, č B, Pereira MP, Contreras L, Cuezva JM, Formentini L, Chronic inhibition of the mitochondrial ATP synthase in skeletal muscle triggers sarcoplasmic reticulum distress and tubular aggregates. Cell Death Dis, 13(6):561(2022) [pubmed]

submitter keyword: Skeletal muscle soleus gastronecmius mice oxphos tubular agregate myopathy

Laura Formentini
contact affiliation	1. Departamento de Biología Molecular, Centro de Biología Molecular ‘“Severo Ochoa’” (CBMSO), c/ Nicolás Cabrera 1, Universidad Autónoma de Madrid, Madrid, Spain. 2. Centro de Investigación Biomédica en red de Enfermedades Raras (CIBERER), ISCIII, Madrid, Spain. 3. Instituto de Investigación Hospital 12 de Octubre, i+12, Universidad Autónoma de Madrid, Madrid, Spain.
contact email	lformentini@cbm.csic.es
lab head
Cristina Sánchez González
contact affiliation	Centro de Biología Molecular Severo Ochoa - Universidad Autónoma de Madrid (CBMSO-UAM)
contact email	cristina.sanchez@cbm.csic.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD026771

PRIDE project URI

• PRIDE
  1. PXD026771
     1. Label: PRIDE project
     2. Name: Skeletal muscle wt and OXPHOS inhibited 18 months-old mice