PXD026729

PXD026729 is an original dataset announced via ProteomeXchange.

Title	In-depth Profiling and Quantification of the Acetylproteome in Hepatocellular Carcinoma with a Trapped Ion Mobility Mass Spectrometer
Description	In this study, we employed an integrated proteomics and acetyl-proteomics strategy to characterize of 8 tumors and 8 matched normal adjacent tissues (NATs) with 4D proteomics technology. Proteomics analysis identified a total of 6551 proteins, of which 5411 proteins were quantified across all samples. A total of 8789 acetylation sites on 2348 proteins were identified, of which 5112 sites of 1620 proteins contained quantitative information.
HostingRepository	PRIDE
AnnounceDate	2022-07-02
AnnouncementXML	Submission_2022-07-02_00:27:45.689.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	jia xu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-15 15:39:47	ID requested
⏵ 1	2022-07-02 00:27:46	announced

Xu J, Guan X, Jia X, Li H, Chen R, Lu Y, In-depth Profiling and Quantification of the Lysine Acetylome in Hepatocellular Carcinoma with a Trapped Ion Mobility Mass Spectrometer. Mol Cell Proteomics, 21(8):100255(2022) [pubmed]

submitter keyword: acetyl-proteomics, cellular metabolism, hepatocellular carcinoma, non-histone, PASEF, proteomics, SIRT2, timsTOF pro

Ruibing Chen
contact affiliation	School of Pharmaceutical Science and Technology, Tianjin University
contact email	rbchen@tju.edu.cn
lab head
jia xu
contact affiliation	tianjin university
contact email	564929283@qq.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/07/PXD026729

PRIDE project URI

• PRIDE
  1. PXD026729
     1. Label: PRIDE project
     2. Name: In-depth Profiling and Quantification of the Acetylproteome in Hepatocellular Carcinoma with a Trapped Ion Mobility Mass Spectrometer