PXD026722 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Skeletal muscle wt and OXPHOS inhibited 18 months-old mice treated with edaravone |
Description | Chronic skeletal muscle mitochondria dyshomeostasis drives tubular aggregate formation. TMT sixplex Isobaric Mass Tagging analysis was carried out in the CBMSO Protein Chemistry Facility (ProteoRed, PRB3-ISCIII and UAM University, Spain. |
HostingRepository | PRIDE |
AnnounceDate | 2022-08-12 |
AnnouncementXML | Submission_2022-08-12_05:17:26.888.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD026722 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Cristina Sánchez González |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-06-15 14:32:10 | ID requested | |
⏵ 1 | 2022-08-12 05:17:27 | announced | |
Publication List
S, á, nchez-Gonz, á, lez C, Herrero Mart, í, n JC, Salegi Ansa B, N, ú, ñ, ez de Arenas C, Stan, č, i, č B, Pereira MP, Contreras L, Cuezva JM, Formentini L, Chronic inhibition of the mitochondrial ATP synthase in skeletal muscle triggers sarcoplasmic reticulum distress and tubular aggregates. Cell Death Dis, 13(6):561(2022) [pubmed] |
Keyword List
submitter keyword: Mouse Skm, soleus, OXPHOS, edaravone, tubular agregate myopathy |
Contact List
Laura Formentini |
contact affiliation | 1. Departamento de Biología Molecular, Centro de Biología Molecular ‘“Severo Ochoa’” (CBMSO), c/ Nicolás Cabrera 1, Universidad Autónoma de Madrid, Madrid, Spain. 2. Centro de Investigación Biomédica en red de Enfermedades Raras (CIBERER), ISCIII, Madrid, Spain. 3. Instituto de Investigación Hospital 12 de Octubre, i+12, Universidad Autónoma de Madrid, Madrid, Spain. (lab head) |
contact email | lformentini@cbm.csic.es |
lab head | |
Cristina Sánchez González |
contact affiliation | Centro de Biología Molecular Severo Ochoa - Universidad Autónoma de Madrid (CBMSO-UAM) |
contact email | cristina.sanchez@cbm.csic.es |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD026722
- Label: PRIDE project
- Name: Skeletal muscle wt and OXPHOS inhibited 18 months-old mice treated with edaravone