PXD026703

PXD026703 is an original dataset announced via ProteomeXchange.

Title	Viral fallout: Semen proteome reveals COVID-19 dysregulates several biological processes linked to male reproductive function
Description	The current global outbreak of COVID-19 has significantly impacted several organ systems. Male reproductive organs are among the potential targets of SARS-CoV-2 infection owing to the presence of abundant viral receptors; ACE2 and TMPRSS2 in the testis. However, the questions pertaining to the long term effects of SARS-CoV-2 infection on male fertility are still unanswered. For this study, we procured the semen samples of COVID-19 recovered patients and performed mass spectrometry based proteomic studies to understand the impact of the disease on the biological processes involved in reproductive health.
HostingRepository	PRIDE
AnnounceDate	2022-05-25
AnnouncementXML	Submission_2022-05-25_09:12:16.623.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Avinash singh
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-14 23:49:59	ID requested
⏵ 1	2022-05-25 09:12:17	announced

Ghosh S, Parikh S, Nissa MU, Acharjee A, Singh A, Patwa D, Makwana P, Athalye A, Barpanda A, Laloraya M, Srivastava S, Parikh F, Semen Proteomics of COVID-19 Convalescent Men Reveals Disruption of Key Biological Pathways Relevant to Male Reproductive Function. ACS Omega, 7(10):8601-8612(2022) [pubmed]

ProteomeXchange project tag: Sars-cov-2, Covid-19

submitter keyword: SARS-CoV-2, COVID-19, Male reproductive function, Proteomics, Semen

Sanjeeva Srivastava
contact affiliation	Proteomics Lab, 304, BSBE Department, Indian Institute Technology Bombay, Powai, Mumbai, India-400076
contact email	sanjeeva@iitb.ac.in
lab head
Avinash singh
contact affiliation	PhD student
contact email	singhavi739@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD026703

PRIDE project URI

• PRIDE
  1. PXD026703
     1. Label: PRIDE project
     2. Name: Viral fallout: Semen proteome reveals COVID-19 dysregulates several biological processes linked to male reproductive function