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PXD026663

PXD026663 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCSF quantitative proteomics reveals potential diagnostic biomarker of pediatric bacterial meningitis
DescriptionIn this study, we performed label-free based CSF quantitative proteomics to identify and analyze the differentially expressed proteins among bacterial meningitis, viral meningitis and hospital controls (children with benign intracranial hypertension). Compared with viral meningitis and hospital controls, we screened 135 differentially expressed proteins to distinguish bacterial meningitis from viral meningitis and controls. Among of them, 69 proteins as potential biomarkers for the diagnosis of bacterial meningitis, including both novel and previously reported candidate protein markers.
HostingRepositoryPRIDE
AnnounceDate2022-05-20
AnnouncementXMLSubmission_2022-05-20_01:54:24.030.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterTing Luo
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-06-11 08:19:56ID requested
12022-05-20 01:54:24announced
Publication List
Luo T, Yang S, Chen Y, Liu S, Yang L, Hu N, Ma Y, Qiu J, Wang K, Li L, Tan L, Quantitative proteomic analysis of cerebrospinal fluid reveals CD163, A2M and full-length APP as potential diagnostic biomarkers of paediatric bacterial meningitis. Proteome Sci, 20(1):8(2022) [pubmed]
Keyword List
submitter keyword: CSF, bacterial meningitis, diagnostic biomarker
Contact List
Liping Li
contact affiliationHunan Children’s Hospital
contact emailliliping118@163.com
lab head
Ting Luo
contact affiliationHunan Children's Hospital
contact emailluoting81@qq.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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