PXD026658

PXD026658 is an original dataset announced via ProteomeXchange.

Title	Surface proteome of large extracellular vesicles
Description	The extracellular vesicle (EV) surface proteome (surfaceome) acts as a fundamental signalling gateway by bridging intra-and extracellular signalling networks, dictates EVs’ capacity to communicate and interact with its the/their environment, and is a source of potential disease biomarkers and therapeutic targets. However, our understanding of surface protein composition of large EVs (100-1000 nm), a major EV-subtype remains limited. Our study provides critical insights into proteins operating at the large interactive platform of L-EVs, and molecular leads for future studies seeking to decipher relatively-understudied L-EV form, heterogeneity and function.
HostingRepository	PRIDE
AnnounceDate	2021-11-17
AnnouncementXML	Submission_2021-11-17_09:02:17.465.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	david greening
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	biotinylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-11 07:24:56	ID requested
⏵ 1	2021-11-17 09:02:17	announced

Dataset with its publication pending

submitter keyword: Surface, interactome, extracellular vesicles, proteomics, large extracellular vesicles

David Greening
contact affiliation	Baker Heart and Diabetes Institute
contact email	david.greening@baker.edu.au
lab head
david greening
contact affiliation	Baker Heart and Diabetes Inst.
contact email	david.greening@baker.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD026658

PRIDE project URI

• PRIDE
  1. PXD026658
     1. Label: PRIDE project
     2. Name: Surface proteome of large extracellular vesicles