PXD026610

PXD026610 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic profiling reveals the molecular changes of insomnia patients
Description	Insomnia is an economic burden and public health problem. This study aimed to explore potential biological pathways and protein networks for insomnia characterized by wakefulness after sleep. Proteomics analysis was performed in the insomnia group with wakefulness and the control group. The differentially expressed proteins (DEPs) were enriched, then hub proteins were identified by protein-protein interaction (PPI) network and verified by parallel reaction monitoring (PRM). Compared with the control group, the sleep time and efficiency of insomnia patients were decreased, awakening time and numbers after sleep onset were significantly increased (P < 0.001).
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:34:41.632.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Guanying Wang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-10 03:01:43	ID requested
1	2022-10-14 02:34:18	announced
⏵ 2	2023-11-14 08:34:42	announced	2023-11-14: Updated project metadata.

Publication List

Liu T, Wang G, Zhang X, Liu X, Liang Z, Ren X, Yan D, Zhang W, B serum proteome profiles revealed dysregulated proteins and mechanisms associated with insomnia patients: A preliminary study. Front Integr Neurosci, 16():936955(2022) [pubmed]

Liu T, Wang G, Zhang X, Liu X, Liang Z, Ren X, Yan D, Zhang W, B serum proteome profiles revealed dysregulated proteins and mechanisms associated with insomnia patients: A preliminary study. Front Integr Neurosci, 16():936955(2022) [pubmed]

Keyword List

submitter keyword: Insomnia
proteomics
immune response
inflammatory reaction
PRM

submitter keyword: Insomnia

proteomics

immune response

inflammatory reaction

PRM

Contact List

Tao Liu
contact affiliation	Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University
contact email	915675629@qq.com
lab head
Guanying Wang
contact affiliation	Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University
contact email	915675629@qq.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD026610
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD026610

PRIDE project URI

Repository Record List

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