PXD026574

PXD026574 is an original dataset announced via ProteomeXchange.

Title	SIRT1 binding proteins in human first trimester villi and HTR8/SVneo cells
Description	In this study, we investigated the potential downstream target proteins in trophoblasts that were regulated by SIRT1 through modulation of acetylation. To this end, the IP products of SIRT1 in the lysate of human first-trimester villous tissue and HTR8/SVneo cells were subjected to proteomics analyses by LC-MS/MS.
HostingRepository	iProX
AnnounceDate	2021-06-08
AnnouncementXML	Submission_2023-02-21_18:31:13.168.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Liling Xiong
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-08 20:50:47	ID requested
1	2021-06-08 20:51:33	announced
⏵ 2	2023-02-21 18:31:14	announced	2023-02-22: Update publication information.

Xiong L, Ye X, Chen Z, Fu H, Li S, Xu P, Yu J, Wen L, Gao R, Fu Y, Qi H, Kilby MD, Saffery R, Baker PN, Tong C, Advanced Maternal Age-associated SIRT1 Deficiency Compromises Trophoblast Epithelial-Mesenchymal Transition through an Increase in Vimentin Acetylation. Aging Cell, 20(10):e13491(2021) [pubmed]

submitter keyword: Coimmunoprecipitation, Tandem mass spectrometry, SIRT1, Human villi, HTR8/SVneo cells

Chao Tong
contact affiliation	Chongqing Medical University
contact email	522010433@qq.com
lab head
Liling Xiong
contact affiliation	Chongqing Medical University
contact email	1029750177@qq.com
dataset submitter

iProX dataset URI