PXD026556

PXD026556 is an original dataset announced via ProteomeXchange.

Title	OCT4 IP-MS in Naive and Primed Human ESCs
Description	Understanding the molecular underpinnings of pluripotency is a prerequisite for optimal maintenance and application of embryonic stem cells (ESCs). While the protein-protein interactions of core pluripotency factors have been identified in mouse ESCs, their interactome in human ESCs (hESCs) has not to date been explored. Here we mapped the OCT4 interactomes in naïve and primed hESCs, revealing extensive connections to mammalian ATP-dependent nucleosome remodeling complexes.
HostingRepository	PRIDE
AnnounceDate	2021-09-12
AnnouncementXML	Submission_2021-09-11_19:38:09.225.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xin Huang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monoacetylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-07 22:55:34	ID requested
⏵ 1	2021-09-11 19:38:10	announced

Huang X, Park KM, Gontarz P, Zhang B, Pan J, McKenzie Z, Fischer LA, Dong C, Dietmann S, Xing X, Shliaha PV, Yang J, Li D, Ding J, Lungjangwa T, Mitalipova M, Khan SA, Imsoonthornruksa S, Jensen N, Wang T, Kadoch C, Jaenisch R, Wang J, Theunissen TW, ve and primed pluripotent states in human. Nat Commun, 12(1):5123(2021) [pubmed]

submitter keyword: OCT4, ESC

Jianlong Wang
contact affiliation	Department of Medicine, Columbia University Irving Medical Center
contact email	jw3925@cumc.columbia.edu
lab head
Xin Huang
contact affiliation	Department of Medicine, Columbia University Irving Medical Center
contact email	xh2200@cumc.columbia.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD026556

PRIDE project URI

• PRIDE
  1. PXD026556
     1. Label: PRIDE project
     2. Name: OCT4 IP-MS in Naive and Primed Human ESCs