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PXD026523

PXD026523 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLenalidomide binding proteins identified by SPIDER assay
DescriptionTo assess whether SPIDER could capture protein-small molecule interaction in a complex environment, here we carried out the SPIDER assay by incubating biotin-Lenalidomide or a biotin control with HEK293T total lysate, followed by the use of biotin conjugated beads coupled with mass spectrometry to identify the interacting proteins
HostingRepositoryiProX
AnnounceDate2021-06-04
AnnouncementXMLSubmission_2023-05-06_00:11:15.964.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXuening Wang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-06-06 22:29:01ID requested
12021-06-06 22:29:24announced
22023-05-06 00:11:16announced2023-05-06: Update publication information.
Publication List
Jiang HW, Chen H, Zheng YX, Wang XN, Meng Q, Xie J, Zhang J, Zhang C, Xu ZW, Chen ZQ, Wang L, Kong WS, Zhou K, Ma ML, Zhang HN, Guo SJ, Xue JB, Hou JL, Liu ZY, Niu WX, Wang FJ, Wang T, Li W, Wang RN, Dang YJ, Czajkowsky DM, Pei J, Dong JJ, Tao SC, Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions. Sci China Life Sci, 66(8):1869-1887(2023) [pubmed]
Keyword List
submitter keyword: Human proteome, , HEK293T, Lenalidomide
Contact List
Shengce Tao
contact affiliationShanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong Universit
contact emailtaosc@sjtu.edu.cn
lab head
Xuening Wang
contact affiliationShanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong Universit
contact emailwxnyoyo@sjtu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI