PXD026404

PXD026404 is an original dataset announced via ProteomeXchange.

Title	Differences in Quantitative Crotonylated Protein Profiling of Human Arterial and Venous Grafts for Coronary Artery Bypass Surgery with Implications to Long-term Patency
Description	The long-term survival of coronary artery bypass grafting (CABG) surgery depends on the patency of the grafts. A key problem is the lower patency of the saphenous vein (SV) compared to the arterial grafts such as internal thoracic artery (ITA) with unclear reasons despite of previous efforts to reveal them. We hypothesized that the intrinsic differences between the ITA and SV may involve the differences in post-translational modification (PTM) of proteins in these two types of vascular grafts. Hence, we applied PTM proteomics to uncover differences between ITA and SV, and to reveal a novel mechanism for the differences in long-term patency.
HostingRepository	iProX
AnnounceDate	2021-06-01
AnnouncementXML	Submission_2021-06-01_19:43:07.576.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Huanxin Chen
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2021-06-01 19:42:17	ID requested
⏵ 1	2021-06-01 19:43:07	announced

Dataset with its publication pending

submitter keyword: CABG, SV, ITV, PTM, Crotonylate

Guowei-He
contact affiliation	Teda International Cardiovascular Hospital
contact email	gwhezj@163.com
lab head
Huanxin Chen
contact affiliation	Teda International Cardiovascular Hospital
contact email	huanxincon@163.com
dataset submitter

iProX dataset URI