PXD026370

PXD026370 is an original dataset announced via ProteomeXchange.

Title	Proteome profiling of brain tissue from multiple system atrophy patients and from controls
Description	Human brain tissue was collected post mortem from patients diagnosed with multiple system atrophy (n=45) and from controls (n=30) in order to perform a comparative quantitative proteome profiling of tissue from the prefrontal cortex (Broadman area 9).
HostingRepository	PRIDE
AnnounceDate	2022-08-12
AnnouncementXML	Submission_2022-08-12_08:18:50.434.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ole Østergaard
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-31 06:57:56	ID requested
⏵ 1	2022-08-12 08:18:51	announced

Rydbirk R, Ø, stergaard O, Folke J, Hempel C, DellaValle B, Andresen TL, L, ø, kkegaard A, Hejl AM, Bode M, Blaabjerg M, M, ø, ller M, Danielsen EH, Salvesen L, Starhof CC, Bech S, Winge K, Rungby J, Pakkenberg B, Brudek T, Olsen JV, Aznar S, Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology. Cell Mol Life Sci, 79(6):336(2022) [pubmed]

submitter keyword: Human, brain tissue, prefrontal cortex, multiple system atrophy, mass spectrometry, proteome, Q-Exactive HF-X

Jesper Velgaard Olsen
contact affiliation	University of Copenhagen, Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Protein Research, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark
contact email	jesper.olsen@cpr.ku.dk
lab head
Ole Østergaard
contact affiliation	Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark
contact email	ole.ostergaard@cpr.ku.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD026370

PRIDE project URI

• PRIDE
  1. PXD026370
     1. Label: PRIDE project
     2. Name: Proteome profiling of brain tissue from multiple system atrophy patients and from controls