PXD026304

PXD026304 is an original dataset announced via ProteomeXchange.

Title	Utilizing of quantitative proteomics to identify species-specific protein therapeutic target for treatment of leishmaniasis.
Description	Identification of common Leishmania antigen proteins is important for practical purposes ranging from diagnostic to the development of a vaccine for the prevention of leishmaniasis. Moreover, we need to establish the potential drug targets that interrupt the replication and transmission of the pathogen to promote drug discovery. Therefore, the objective of this work was to provide the public proteome database which would be useful for the establishment of novel protein antigenicity for therapeutic purposes. This information would introduce the alternative protein targets for Leishmaniasis, allowing the development of therapeutic strategies for the disease.
HostingRepository	PRIDE
AnnounceDate	2022-05-20
AnnouncementXML	Submission_2022-05-19_23:45:59.249.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD026304
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Sucheewin Krobthong
SpeciesList	scientific name: Leishmania donovani Ld 2001; NCBI TaxID: 1215323;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-27 02:37:23	ID requested
⏵ 1	2022-05-19 23:46:00	announced

Krobthong S, Yingchutrakul Y, Samutrtai P, Hitakarun A, Siripattanapipong S, Leelayoova S, Mungthin M, Choowongkomon K, Utilizing Quantitative Proteomics to Identify Species-Specific Protein Therapeutic Targets for the Treatment of Leishmaniasis. ACS Omega, 7(15):12580-12588(2022) [pubmed]

submitter keyword: LC-MS/MS

orbitrap

antigenic molecules

Kiattawee Choowongkomon
contact affiliation	1.Department of Biochemistry, Faculty of Science, Kasetsart University, 50 Ngam Wong Wan Road, Chatuchak, Bangkok 10900, Thailand 2.Center for Advanced Studies in Nanotechnology for Chemical, Food and Agricultural Industries, KU Institute for Advanced Studies, Kasetsart University, Bangkok, 10900, Thailand
contact email	fsciktc@ku.ac.th
lab head
Sucheewin Krobthong
contact affiliation	National Science and Technology Development Agency
contact email	sucheewin82@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD026304

PRIDE project URI

• PRIDE
  1. PXD026304
     1. Label: PRIDE project
     2. Name: Utilizing of quantitative proteomics to identify species-specific protein therapeutic target for treatment of leishmaniasis.