PXD026302

PXD026302 is an original dataset announced via ProteomeXchange.

Title	Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant
Description	Here we use unbiased abundance proteomics and phosphoproteomics to assess global changes to host and viral proteins in Calu-3 cells at 10 and 24 hours post infection with either the B.1.1.7 UK variant or early-lineage SARS-CoV-2 viruses VIC and IC19.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:31:00.700.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mehdi Bouhaddou
SpeciesList	scientific name: Severe acute respiratory syndrome coronavirus 2; NCBI TaxID: NCBITaxon:2697049; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-27 00:30:47	ID requested
1	2022-01-20 12:30:46	announced
⏵ 2	2024-10-22 05:31:01	announced	2024-10-22: Updated project metadata.

10.1038/s41586-021-04352-y;

Thorne LG, Bouhaddou M, Reuschl AK, Zuliani-Alvarez L, Polacco B, Pelin A, Batra J, Whelan MVX, Hosmillo M, Fossati A, Ragazzini R, Jungreis I, Ummadi M, Rojc A, Turner J, Bischof ML, Obernier K, Braberg H, Soucheray M, Richards A, Chen KH, Harjai B, Memon D, Hiatt J, Rosales R, McGovern BL, Jahun A, Fabius JM, White K, Goodfellow IG, Takeuchi Y, Bonfanti P, Shokat K, Jura N, Verba K, Noursadeghi M, Beltrao P, Kellis M, Swaney DL, Garc, í, a-Sastre A, Jolly C, Towers GJ, Krogan NJ, Evolution of enhanced innate immune evasion by SARS-CoV-2. Nature, 602(7897):487-495(2022) [pubmed]

ProteomeXchange project tag: Sars-cov-2, Covid-19

submitter keyword: SARS-CoV-2, virus, variants, systems biology

Nevan J. Krogan
contact affiliation	Department of Cellular and Molecular Pharmacology, UCSF
contact email	nevan.krogan@ucsf.edu
lab head
Mehdi Bouhaddou
contact affiliation	UCSF
contact email	mehdibouhaddou@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/01/PXD026302

PRIDE project URI

• PRIDE
  1. PXD026302
     1. Label: PRIDE project
     2. Name: Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant