PXD026274

PXD026274 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Multi-Omics signature of Autism Spectral Disorder reveals microbial macromolecules
Description	Changes in gut microbiota have been implicated in pathophysiology and cognitive capabilities of patients suffering from autism spectrum disorder. Yet, factors that mediate this interaction remain not fully understood. In this study, we analyzed stool samples from sever autistic pediatric patients and healthy individuals. Using multi omics platforms, we characterized microbiota diversities, proteins, and possible altered metabolic pathways.
HostingRepository	PRIDE
AnnounceDate	2025-01-29
AnnouncementXML	Submission_2025-01-29_09:18:12.610.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sameh Magdeldin
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; deamidated residue
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-26 04:42:33	ID requested
⏵ 1	2025-01-29 09:18:13	announced

Publication List

10.1016/j.jare.2025.01.036;
Osama A, Anwar AM, Ezzeldin S, Ahmed EA, Mahgoub S, Ibrahim O, Ibrahim SA, Abdelhamid IA, Bakry U, Diab AA, A Sayed A, Magdeldin S, Integrative multi-omics analysis of autism spectrum disorder reveals unique microbial macromolecules interactions. J Adv Res, ():(2025) [pubmed]

10.1016/j.jare.2025.01.036;

Osama A, Anwar AM, Ezzeldin S, Ahmed EA, Mahgoub S, Ibrahim O, Ibrahim SA, Abdelhamid IA, Bakry U, Diab AA, A Sayed A, Magdeldin S, Integrative multi-omics analysis of autism spectrum disorder reveals unique microbial macromolecules interactions. J Adv Res, ():(2025) [pubmed]

Keyword List

submitter keyword: Autism, Meta-proteomics, disorders, Meta-genomics, MultiOmics

submitter keyword: Autism, Meta-proteomics, disorders, Meta-genomics, MultiOmics

Contact List

Sameh Magdeldin
contact affiliation	Proteomics and Metabolomics Research Program, Basic Research Unit, Research Department, Children’s Cancer Hospital Egypt, Cairo, 57357, Egypt
contact email	Sameh.Magdeldin@57357.org
lab head
Sameh Magdeldin
contact affiliation	Proteomics and Metabolomics Research Program, Basic Research Department, Children’s Cancer Hospital, (CCHE-57357), Cairo 57357, Egypt
contact email	proteomicslab2017@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD026274
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD026274

PRIDE project URI

Repository Record List

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