PXD026260

PXD026260 is an original dataset announced via ProteomeXchange.

Title	Brain tissus of Oryzias melastigma under hypoxia, rep2
Description	Hypoxia is amongst the most widespread and pressing problems in aquatic environments. Here we demonstrate that fish (Oryzias melastigma) exposed to hypoxia show reproductive impairments (retarded gonad development, decrease in sperm count and sperm motility) in F1 and F2 generations despite these progenies (and their germ cells) having never been exposed to hypoxia. We further show that the observed transgenerational reproductive impairments are associated with a differential methylation pattern of specific genes in sperm of both F0 and F2 coupled with relevant transcriptomic and proteomic alterations, which may impair spermatogenesis.
HostingRepository	PRIDE
AnnounceDate	2024-10-11
AnnouncementXML	Submission_2024-10-11_03:11:08.754.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tong Yin
SpeciesList	scientific name: Oryzias latipes (Japanese rice fish) (Japanese killifish); NCBI TaxID: 8090;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-25 08:52:38	ID requested
⏵ 1	2024-10-11 03:11:09	announced

Dataset with its publication pending

submitter keyword: hypoxia

Dr. Ball KP LAI
contact affiliation	City University of Hong Kong
contact email	kengplai@cityu.edu.hk
lab head
Tong Yin
contact affiliation	The University of Hong Kong
contact email	tongyin9002@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/05/PXD026260

PRIDE project URI

• PRIDE
  1. PXD026260
     1. Label: PRIDE project
     2. Name: Brain tissus of Oryzias melastigma under hypoxia, rep2