PXD026100

PXD026100 is an original dataset announced via ProteomeXchange.

Title	Effect of HPV8-E7 expression on the secretome of keratinocytes
Description	Human papillomavirus type 8 (HPV8) is associated with the development of non-melanoma skin cancer. In the past we already delved into the mechanisms involved in keratinocyte invasion, showing that the viral E7 oncoprotein is a key player that drives invasion of basal keratinocytes controlled by the extracellular protein fibronectin. To unravel further downstream effects in E7 expressing keratinocytes we now characterized alterations of the secretome of E7 expressing N/TERT keratinocytes.
HostingRepository	PRIDE
AnnounceDate	2022-02-17
AnnouncementXML	Submission_2022-02-17_03:52:30.639.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Prerana Wagle
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-19 22:34:17	ID requested
⏵ 1	2022-02-17 03:52:31	announced

Kirschberg M, Syed AS, D, ö, nmez HG, Heuser S, Wilbrand-Hennes A, Alonso A, Hufbauer M, Akg, ü, l B, Novel Insights Into Cellular Changes in HPV8-E7 Positive Keratinocytes: A Transcriptomic and Proteomic Analysis. Front Microbiol, 12():672201(2021) [pubmed]

submitter keyword: Human papillomavirus type 8 (HPV8), E7 oncoprotein, secretome, keratinocyte transformation

Baki Akgül
contact affiliation	Institute of Virology, University of Cologne Medical Faculty and University Hospital Cologne, Cologne, Germany
contact email	baki.akguel@uk-koeln.de
lab head
Prerana Wagle
contact affiliation	CECAD Research Center
contact email	proteomics-facility@uni-koeln.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD026100

PRIDE project URI

• PRIDE
  1. PXD026100
     1. Label: PRIDE project
     2. Name: Effect of HPV8-E7 expression on the secretome of keratinocytes