PXD026095

PXD026095 is an original dataset announced via ProteomeXchange.

Title	The human and mouse islet peptidome: effects of obesity and type 2 diabetes
Description	To characterise the impact of metabolic disease on the peptidome of human and mouse pancreatic islets and the contribution of intra-islet glucagon-like peptide 1 (GLP-1) receptor signalling.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:24:50.146.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD026095
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Richard Kay
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	amidated residue; 2-pyrrolidone-5-carboxylic acid (Gln); acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-19 09:00:15	ID requested
1	2021-08-24 07:03:48	announced
2	2021-08-25 00:39:08	announced	2021-08-25: Updated project metadata.
⏵ 3	2024-10-22 05:24:51	announced	2024-10-22: Updated project metadata.

10.6019/PXD026095;

10.1021/acs.jproteome.1c00463;

Galvin SG, Kay RG, Foreman R, Larraufie P, Meek CL, Biggs E, Ravn P, Jermutus L, Reimann F, Gribble FM, The Human and Mouse Islet Peptidome: Effects of Obesity and Type 2 Diabetes, and Assessment of Intraislet Production of Glucagon-like Peptide-1. J Proteome Res, 20(9):4507-4517(2021) [pubmed]

submitter keyword: peptidomics, type 2 diabetes, glucagon, islets, insulin

Professor Fiona Gribble
contact affiliation	Wellcome Trust MRC Institute of Metabolic Science
contact email	fmg23@cam.ac.uk
lab head
Richard Kay
contact affiliation	University of Cambridge
contact email	rgk27@medschl.cam.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD026095

PRIDE project URI

• PRIDE
  1. PXD026095
     1. Label: PRIDE project
     2. Name: The human and mouse islet peptidome: effects of obesity and type 2 diabetes