PXD025922

PXD025922 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Protein profiling of Aortic-Valvular and Endocardial endothelial cells using label-free proteomics
Description	The variations in the protein profile of aortic-valvular (AVE) and endocardial endothelial (EE) cells are currently unknown. The current study's objective is to identify differentially expressed proteins and associated pathways in both endothelial cells. We used endothelial cells isolated from the porcine aortic valve and endocardium for the profiling of proteins. Label-free proteomics was performed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Our proteomics analysis revealed that 29 proteins were highly expressed, and 25 proteins were less represented in the valve than endocardial endothelium. The first part of the study was already available in the ProteomeXchange Consortium (PXD009194).
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:32:42.834.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD025922
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	MAHESH CHANDRAN V R
SpeciesList	scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Synapt MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-10 23:12:48	ID requested
1	2022-02-17 03:32:03	announced
⏵ 2	2024-10-22 05:32:50	announced	2024-10-22: Updated project metadata.

Publication List

Aneesh Kumar A, Ajith Kumar GS, Satheesh G, Surendran A, Chandran M, Kartha CC, Jaleel A, Proteomics Analysis Reveals Diverse Molecular Characteristics between Endocardial and Aortic-Valvular Endothelium. Genes (Basel), 12(7):(2021) [pubmed]
10.3390/genes12071005;
10.6019/PXD025922;

Aneesh Kumar A, Ajith Kumar GS, Satheesh G, Surendran A, Chandran M, Kartha CC, Jaleel A, Proteomics Analysis Reveals Diverse Molecular Characteristics between Endocardial and Aortic-Valvular Endothelium. Genes (Basel), 12(7):(2021) [pubmed]

10.3390/genes12071005;

10.6019/PXD025922;

Keyword List

submitter keyword: Endocardial endothelial (EE) cells ,Aortic-valvular (AVE), LC-MS/MS

submitter keyword: Endocardial endothelial (EE) cells ,Aortic-valvular (AVE), LC-MS/MS

Contact List

Dr.Abdul Jaleel K.A
contact affiliation	Scientist F Cardiovascular Diseases & Diabetes Biology Kerala ,Rajiv gandhi centre for Biotechnology,Kerala, India
contact email	jaleel@rgcb.res.in
lab head
MAHESH CHANDRAN V R
contact affiliation	Technician, Mass spectrometry and proteomics core facility, RGCB
contact email	maheshchandran@rgcb.res.in
dataset submitter

Full Dataset Link List

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PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD025922

PRIDE project URI

Repository Record List

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