PXD025903

PXD025903 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Trifunctional PIP3 binder identification
Description	Trifunctional PIP3 is a chemically modified derivate of PIP3 that includes 3 functionalized groups allowing spacial an temporal manipulation of its release and function. A caged group allows for timed release of the coumpound, a cross-linking group induces covalent binding to binders, while a clickable group is used for specific pull=out using functionilized beads. These functionalities comibend create a precise discovery tool used to detect PIP3 interactors.
HostingRepository	PRIDE
AnnounceDate	2025-02-19
AnnouncementXML	Submission_2025-02-19_10:06:50.819.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ana Kojic
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-09 07:53:13	ID requested
⏵ 1	2025-02-19 10:06:51	announced

Publication List

10.1002/anie.202103599;
M, ü, ller R, Kojic A, Citir M, Schultz C, Synthesis and Cellular Labeling of Multifunctional Phosphatidylinositol Bis- and Trisphosphate Derivatives. Angew Chem Int Ed Engl, 60(36):19759-19765(2021) [pubmed]

10.1002/anie.202103599;

M, ü, ller R, Kojic A, Citir M, Schultz C, Synthesis and Cellular Labeling of Multifunctional Phosphatidylinositol Bis- and Trisphosphate Derivatives. Angew Chem Int Ed Engl, 60(36):19759-19765(2021) [pubmed]

Keyword List

submitter keyword: HeLa, PIP3, trifunctional

submitter keyword: HeLa, PIP3, trifunctional

Contact List

Carsten Schultz
contact affiliation	Helen Jo Whitsell Endowed Professor and Chair Department of Chemical Physiology and Biochemistry, OHSU, Portland OR, USA
contact email	schulcar@ohsu.edu
lab head
Ana Kojic
contact affiliation	EMBL, OHSU
contact email	ana.kojic@embl.de
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD025903
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD025903

PRIDE project URI

Repository Record List

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